Analysis and computer program for rupture-risk prediction of abdominal aortic aneurysms

Analysis and computer program for rupture-risk prediction of abdominal aortic aneurysms

BACKGROUND Ruptured abdominal aortic aneurysms (AAAs) are the 13th leading cause of death in the United States. While AAA rupture may occur without significant warning, its risk assessment is generally based on critical values of the maximum AAA diameter (> 5 cm) and AAA-growth rate (> 0.5 cm/year). These criteria may be insufficient for reliable AAA-rupture risk assessment especially when pred...

Commentary: Computational Biomechanics-Based Rupture Prediction of Abdominal Aortic Aneurysms.

Biomechanical prediction of abdominal aortic aneurysm rupture risk: Sensitivity analysis

Objectives: The purpose of this research is to determine the quantitative relationship between the peak wall stress of abdominal aortic aneurysm (AAA) and its clinical risk factors including its maximum diameter, asymmetry index, wall thickness and abnormal high blood pressure. Methods: The response surface experimental design with one response and four variables was used to design the experime...

Biomechanical rupture risk assessment of abdominal aortic aneurysms based on a novel probabilistic rupture risk index.

A rupture risk assessment is critical to the clinical treatment of abdominal aortic aneurysm (AAA) patients. The biomechanical AAA rupture risk assessment quantitatively integrates many known AAA rupture risk factors but the variability of risk predictions due to model input uncertainties remains a challenging limitation. This study derives a probabilistic rupture risk index (PRRI). Specificall...

Risk Factors for Abdominal Aortic Aneurysms

Background—Abdominal aortic aneurysm is an asymptomatic condition with a high mortality rate related to rupture. Methods and Results—In a cohort of 2035 men and 2310 women in Tromsø, Norway, who were 25 to 82 years old in 1994, the authors identified risk factors for incident abdominal aortic aneurysm over the next 7 years. The impact of smoking was studied in particular. Ultrasound examination...